Robbed of Meaning?

Published as a Letter to the Editor in the Westmount Independent, 16 April 2024 The Police Report (April 2, 2024, p10) headline “‘Flash mob’ thieves rob Sherbrooke boutique…” left me confused. Are the perpetrators thieves, or are they robbers? Fortunately, the body of the article helped to clear up the…

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HamNN Classification Results with Publicly Available Datasets

These datasets are included in the VhamNN and HamNN repositories on GitHub. It should be noted that the formula for balanced accuracy is different for binary classification problems and multiclass classification. HamNN Classification Results with Publicly Available Datasets Filename classes discrete attibutes continuous attributes total instances missing values (%) best…

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instalment 9: prescription medications that may be helpful in certain situations

Metformin, a medication which costs pennies a day, lowers insulin levels and has been shown to have powerful effects against a host of disorders including cancer, cardiovascular disease, brain and kidney disorders, obesity, as well as inflammation. But there is reason to believe that many players in the health care industry, prefer that you not know this.

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COVID-19 mortality and vaccine efficacy in nursing homes: does vitamin B12 deficiency play a role?

Henry Olders, P.Eng, MD, FRCPC Affiliate Member, Dept of Psychiatry, McGill University, Montreal, Canada Abstract It is believed that nursing home residents experience more disease severity and higher mortality from COVID-19, compared to community-dwelling elderly with similar comorbidities. Among the possible explanations for this phenomenon is the difference in vitamin…

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Are cyclists out to kill?

Published on linkedin.com on 2015-11-18 In Montreal these days, with later sunrises and early sunsets, many cycling commuters are going to and from work in the dark. I don’t know if this is particular to Montreal, but many of these cyclists have no lights on their bicycles, and additionally wear…

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Response to Recommendations to Increase Dietary Protein Intake During Chemotherapy

Articles supplied: Arends J, Bachmann P, Baracos V et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr. 2017;36:11-48. Stobäus N, Müller MJ, Küpferling S, Schulzke JD, Norman K. Low Recent Protein Intake Predicts Cancer-Related Fatigue and Increased Mortality in Patients with Advanced Tumor Disease Undergoing Chemotherapy. Nutr Cancer.…

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Why do mammalian males have scrota?

My hypothesis is that the scrotum, which in mammals, is often exposed, relatively hairless, and with thin skin and little subcutaneous tissue, may have evolved for perhaps a different reason than simply to provide a lower temperature for spermatogenesis. Consider that humans produce about 25,000 sperm every minute. Why so many?…

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Do PPIs suppress B12?

This letter to the Editor was published in the November 2001 issue of Parkhurst Exchange, p7 Gentlemen: In the June 2001 issure of Parkhurst Exchange, your consultant AS reported no serious side effects from the longterm use of pantoprazole, to his knowledge. Gastric acid suppressive therapy in general has been…

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The role of diet in gout

Gout is caused by an excess of uric acid (urate) in the system, which can then form crystals in various places, including the joint of the big toe. Crystals in the joint cause inflammation and pain. Excess uric acid can be due to excessive dietary intake of purines, insufficient urinary…

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Dealing with difficult patients

Version française General principles for dealing with difficult patients who are cognitively intact As caregivers, we often find ourselves extending ourselves for our patients, “going the extra mile”. This works well when the patient is appreciative of our efforts: we feel good about ourselves. But if our efforts are not…

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Traiter les patients difficiles

English version Principes généraux relatifs aux traitements des patients difficiles dont la fonction cognitive est intacte En tant que soignant professionnel, nous devons souvent nous dévouer “corps et âme” pour nos patients.  C’est très valorisant de savoir à quel point nos patients apprécient et qu’ils nous témoignent leur reconnaissance. Toutefois,…

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Commentary on the book “Deadly medicines and organized crime: how big pharma has corrupted healthcare” by Dr. Peter Gøtzsche

I’ve been reading a most interesting book, titled “Deadly medicines and organized crime: how big pharma has corrupted healthcare,” by Dr. Peter Gøtzsche. Dr. Gøtzsche, a specialist in internal medicine and professor at the University of Copenhagen, co-founded the Cochrane Collaboration in 1993 and established the Nordic Cochrane Centre. The…

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Methionine content of food items

To facilitate following a methionine restriction diet, I’ve put together a Filemaker “solution” (Filemaker’s name for a database using their platform) which will provide you with the methionine content for the majority of the items in the USDA nutrients database, version SR27. The solution also includes the content of cysteine,…

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Senate reform in Canada

With the Mike Duffy trial figuring prominently in the news these days, The NDP is renewing calls for abolition of the Senate. Instead of outright abolition of the “House of sober second thought” perhaps a major restructuring should be considered. Here is one suggestion: Reduce the size of the senate,…

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A disappointing symposium: McConnell Brain Imaging Centre 30th Anniversary

Yesterday I attended an all-day symposium at the Montreal Neurological Institute, to celebrate the 30th anniversary of the founding of the McConnell Brain Imaging Centre. I went to hear talks by David Van Essen, Principal Investigator, The Human Connectome Project; Henry Markram, Director, The Blue Brain Project, and Coordinator, The Human Brain Project; and Robert…

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Methionine Restriction abstracts

Grandison, R. C., M. D. Piper, and L. Partridge (2009) Nature 462:1061-1064. Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Dietary restriction extends healthy lifespan in diverse organisms and reduces fecundity. It is widely assumed to induce adaptive reallocation of nutrients from reproduction to somatic maintenance, aiding…

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Research Proposal: Treating Cancer-Related Anorexia-Cachexia
 with a Methionine Restricted Diet

Henry Olders, MD November 6, 2013 Research Proposal: Treating Cancer-Related Anorexia-Cachexia with a Methionine Restricted Diet Anorexia and cachexia are frequent concomitants of the later stages of cancer, and contribute significantly to poor quality of life (QOL). Moreover, family members and friends of cancer patients with anorexia and cachexia are…

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The war against Islamic State

Western democracies are lining up to engage in bombing raids against Islamic State installations, citing the IS (aka ISIS, or ISIL) terrorists as particularly cruel and barbaric, a scourge that needs to be eliminated. We’ve seen the gruesome beheadings, and heard the warnings that Canadians may become radicalized, join IS,…

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Assisted suicide

In Canada and Quebec, the debate over the right to die with dignity, medically assisted suicide, and euthanasia is often heated. I am struck by the inconsistency, perhaps even hypocrisy, of governments that maintain that it is OK for individuals to commit suicide, but not to receive help from anyone…

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Why we get old and die, and what to do about it

This presentation was most recently given at the Westmount Healthy City Project, on 2015-10-29.  It was also presented at: Institut universitaire en santé mentale Douglas Grand Rounds, 2013-5-23 Jewish General Hospital Department of Psychiatry Clinical Grand Rounds, 2012-4-12 McGill Geriatric Medicine Grand Rounds, Montreal General Hospital, 2012-1-24 Ste. Anne’s Hospital, Continuing…

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Letter to the Editor: Comment on ‘Acute Impact of Immediate Release Methylphenidate Administered Three Times a Day on Sleep in Children with Attention-Deficit/Hyperactivity Disorder’

The study reported on in the article “Acute impact of immediate release methylphenidate administered three times a day on sleep in children with attention-deficit/hyperactivity disorder” (Corkum, Panton, Ironside, Macpherson, & Williams, 2008) found a significant reduction in total sleep time of almost an hour with medication compared to the no…

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Letter to the Editor: PPIs, B12, and falls. Comment on ‘Use of proton pump inhibitors and risk of osteoporosis-related fractures’

This letter to the editor of the “Canadian Medical Association Journal” was published electronically on the CMAJ website, on 2008-11-18, in response to this article:  Targownik LE, Lix LM, Metge CJ, Prior HJ, Leung S, Leslie WD. Use of proton pump inhibitors and risk of osteoporosis-related fractures. CMAJ. 2008;179:319-326. Article…

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Depression in Long Term Care

This presentation was given on 2008-11-17 at Ste. Anne’s Hospital in the Department of Psychiatry Conference Series, and on 2008-11-20 to the Head Nurses at Ste. Anne’s Hospital. It had previously been presented to staff of CSSS Cavendish on 2008-10-8, at Centre d’Accueil Henri-Bradet. Download a pdf of the slides and…

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How to discourage gas consumption

Letter to the Editor, submitted to the Montreal Gazette on 2008-8-28. Many companies provide parking at no charge for their employees. This represents a subsidy, as parking spaces involve considerable costs including initial construction, drainage, paving, lighting as well as ongoing expenses such as snow removal, security, and electricity. Never…

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Too much, too late?

Letter to the Editor of the Montreal Gazette. It appeared in the 2006-11-24 edition under the heading “Puerile bullyboy”. Dan McTeague criticises Prime Minister Harper (letters, 23 Nov 2006) for “openly” chastising China on its human-rights record and bringing up the case of Huseyin Celil, then complains that he should…

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Does a fish a day keep the doctor away? The role of omega-3 fatty acids in psychiatry

This presentation was given on 2006-9-5 at Ste. Anne’s Hospital, Ste-Anne-de-Bellevue, Québec. Earlier versions of this talk were presented at: • Consultation-Liaison Psychiatry Rounds, Sir Mortimer B. Davis – Jewish General Hospital, 2002-6-28 • Department of Psychiatry Clinical Grand Rounds, Sir Mortimer B. Davis – Jewish General Hospital, 2002-9-12 •…

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Does too much sleep cause depression?

Presented at Ste. Anne’s Hospital 2006-5-9 and on 2006-6-1. Some proverbs about sleep: “One hour’s sleep before midnight is worth two hours after.”
—John Rays (1627-1705): A Compleat Collection of English Proverbs, 1670 “Plough deep while sluggards sleep.”
—Benjamin franklin (1706-1790): Maxim prefixed to Poor Richard’s Almanac, 1757 “The early bird catches…

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“Sleeper cells”

Letter to the Editor of the Montreal Gazette. It appeared in the 2006-3-8 edition under the heading “Lack of vitamin B12 also causes lesions”. The article “Brain’s ‘sleeper cells’ stalking boomers” (7 mar 2006) points out that white matter lesions in the brain predict stroke and dementia. It fails to…

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hammingNN progress report

Since my medical school days, I’ve been mulling over some ideas for artificial neural networks that adhere more closely to the physiology that I studied. Over the past couple of years, I finally implemented those ideas, using the Forth programming language on a Macintosh. The process went considerably faster than…

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Ritalin (methylphenidate)

Ritalin • -more effective than sertraline in improving cognitive function and maintaining alertness in patients with traumatic brain injury (Lee H 20 p97) • better tolerated than sertraline (ibid.) • -found effective in hypoactive delirium, apathy, depressive syndrome (Meyers BJ 148 1738) • -accelerates antidepressant response in elderly (Lavretsky H…

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Journal club: olfactory perception, communication, and the nose-to-brain pathway

Consultation-Liaison Rounds, 05-3-3, at the SMBD – Jewish General Hospital Article: Stockhorst, U., and R. Pietrowsky (2004) Physiol Behav 83:3-11. Olfactory perception, communication, and the nose-to-brain pathway. Abstract: The present paper’s aim is of to give an overview about the basic knowledge as well as actual topics of olfaction–with a…

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