Do PPIs suppress B12?

This letter to the Editor was published in the November 2001 issue of Parkhurst Exchange, p7 Gentlemen: In the June 2001 issure of Parkhurst Exchange, your consultant AS reported no serious side effects from the longterm use of pantoprazole, to his knowledge. Gastric acid suppressive therapy in general has been…

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Comment on: White matter, red flag (letter to the editor, Parkhurst Exchange, sent 2010-4-12)

The Q&A response to the question “What could multiple hyperdensities on brain MRI in the absence of migraine indicate?” (Parkhurst Exchange, April 2010, p28) did not include B12 deficiency as a possible cause. There are a number of case reports (1-4) reporting the finding of white matter hyperintensities on T2-weighted…

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Comment on “Age-related macular degeneration” (letter to the editor, Parkhurst Exchange, submitted 2008-11-25)

The article “Age-related macular degeneration” Oct 2008, p52) lists the risk factors for AMD as age, genetics, history of smoking, Caucasian race, and diet low in antioxidants. Not mentioned was the association between a lower risk of AMD and higher fish and/or omega-3 fatty acid consumption. Augood C, Chakravarthy U,…

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Methionine Restriction abstracts

Grandison, R. C., M. D. Piper, and L. Partridge (2009) Nature 462:1061-1064. Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Dietary restriction extends healthy lifespan in diverse organisms and reduces fecundity. It is widely assumed to induce adaptive reallocation of nutrients from reproduction to somatic maintenance, aiding…

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Research Proposal: Treating Cancer-Related Anorexia-Cachexia
 with a Methionine Restricted Diet

Henry Olders, MD November 6, 2013 Research Proposal: Treating Cancer-Related Anorexia-Cachexia with a Methionine Restricted Diet Anorexia and cachexia are frequent concomitants of the later stages of cancer, and contribute significantly to poor quality of life (QOL). Moreover, family members and friends of cancer patients with anorexia and cachexia are…

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